KD-Validated Anti NDUFB9 Antibody, clone 24GB90, Rabbit Monoclonal

The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

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A synthesized peptide corresponding to a sequence within amino acids 50-200 of human NDUFB9 [NP_004996.1].

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.