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Merck
CN

SAB6012456

KD-Validated Anti Ubiquitin Specific Peptidase 5 Antibody, clone 24GB2480, Rabbit Monoclonal

newenhanced validation

clone 24GB2480, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

IsoT

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About This Item

UNSPSC Code:
12352203

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB2480, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

96 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

1 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000111667

NCBI accession no.

NP_001092006.1

UniProt accession no.

P45974

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... USP5(8078)

General description

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 770-835 of human USP5 [NP_001092006.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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