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SAB6012469

KD-Validated Anti Chromodomain helicase DNA binding protein 3 Antibody, clone 23GB1305, Rabbit Monoclonal

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clone 23GB1305, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

HZFH, MI-2A, SNIBCPS, ZFH

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About This Item

UNSPSC Code:
12352203
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Product Name

KD-Validated Anti Chromodomain helicase DNA binding protein 3 Antibody, clone 23GB1305, Rabbit Monoclonal, clone 23GB1305, recombinant rabbit monoclonal, expressed in HEK293 cells

biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB1305, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

226 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

Gene Information

human ... CHD3(1107)

sustainability

Greener Alternative Product

concentration

1.25 mg/ml

technique(s)

immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

NCBI accession no.

UniProt accession no.

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shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 220-300 of human CHD3 [NP_001005273.1].

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

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