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Merck
CN

SAB6012499

KD-Validated Anti CDC73 Antibody, clone 23GB3450, Rabbit Monoclonal

newenhanced validation

clone 23GB3450, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

C1ORF28, FIHP, HPTJT, HRPT2, HYX

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit (Monoclonal)

Quality Level

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB3450, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

61 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

0.8 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDC73(79577)

General description

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3′ mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 350-400 of human HRPT2 / CDC73 [NP_078805.3].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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