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Merck
CN

SAB6012528

KD-Validated Anti MAP3K2 Antibody, clone 24GB260, Rabbit Monoclonal

newenhanced validation

clone 24GB260, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

MAPKKK2, MEKK 2, MEKK2B

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB260, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

70 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.6 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:4,000-1:20,000

isotype

IgG

Ensembl | human accession no.

ENSG00000169967

NCBI accession no.

NP_006600.3

UniProt accession no.

Q9Y2U5

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAP3K2(10746)

General description

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1-54 of human MEKK2 [NP_006600.3].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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