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Merck
CN

SAB6012536

KD-Validated Anti SMC3 Antibody, clone 24GB2155, Rabbit Monoclonal

newenhanced validation

clone 24GB2155, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

BAM, CDLS3, CSPG6, HCA, SMC3L1

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB2155, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

142 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.5 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000108055

NCBI accession no.

NP_005436.1

UniProt accession no.

Q9UQE7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SMC3(9126)

General description

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1150-1217 of human SMC3 [NP_005436.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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