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SBR00063

Danofloxacin Mesylate

≥98% (HPLC), powder

Synonym(s):

CP-76136-27, Danofloxacin methanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C20H24FN3O6S
CAS Number:
119478-55-6
Molecular Weight:
453.48
UNSPSC Code:
51101500
NACRES:
NA.41
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

off-white to yellow

mp

>300 °C

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycoplasma

application(s)

advanced drug delivery

mode of action

DNA synthesis | inhibits

storage temp.

2-8°C

SMILES string

CN1C[C@@H]2C[C@H]1CN2C3=C(C=C4C(=C3)N(C=C(C4=O)C(=O)O)C5CC5)F.CS(=O)(=O)O

InChI

1S/C19H20FN3O3.CH4O3S/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10;1-5(2,3)4/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26);1H3,(H,2,3,4)/t11-,12-;/m0./s1

InChI key

APFDJSVKQNSTKF-FXMYHANSSA-N

General description

Danofloxacin Mesylate is a synthetic, broad-spectrum fluoroquinolone with antibacterial activity. Danofloxacin Mesylate exerts its antibacterial activity by inhibiting DNA gyrase and topoisomerase IV, enzymes that are essential for bacterial DNA synthesis and replication.

Application

Have been studied for their applications as scaffolds for the development of new antibiotics and other drugs targeting bacterial DNA gyrase and topoisomerase IV.

Biochem/physiol Actions

Danofloxacin Mesylate inhibits bacterial DNA synthesis by interfering with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Danofloxacin Mesylate is active against Gram-negative, Gram-positive bacteria, mycoplasma.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H373,H412

Hazard Classifications

Aquatic Chronic 3 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000364024
0000364024

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Global Trade Item Number

SKUGTIN
SBR00063-50MG04065271160484