SBR00075
Avibactam Sodium Salt
≥97% (HPLC), powder
Synonym(s):
NXL-104
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About This Item
Empirical Formula (Hill Notation):
C7H11N3NaO6S
CAS Number:
Molecular Weight:
288.23
UNSPSC Code:
51101500
NACRES:
NA.41
Quality Segment
assay
≥97% (HPLC)
form
powder
storage condition
under inert gas (Nitrogen)
color
white
antibiotic activity spectrum
Gram-negative bacteria
application(s)
advanced drug delivery
mode of action
enzyme | inhibits
shipped in
ambient
storage temp.
−20°C
SMILES string
C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
InChI
InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
InChI key
RTCIKUMODPANKX-JBUOLDKXSA-M
General description
Avibactam sodium is a β-lactamase inhibitor and β-Lactamases are responsible for resistance to penicillins, monobactams, carbapenems, and extended-spectrum cephalosporins. It is a synthetic molecule with activity against gram-negative bacteria.
Application
Avibactam and related compounds have been studied for their ability to inhibit a variety of beta-lactamases, which are enzymes that inactivate beta-lactam antibiotics such as penicillin. The development of new beta-lactamase inhibitors like Avibactam is important for combating antibiotic resistance.
Biochem/physiol Actions
Avibactam is a β-lactamase inhibitor which inhibits the activity of β-lactamases by binding to the active site of β-lactamases and blocks the access of the substrate to the enzyme. Avibactam is effective against bacteria resistant to ceftazidime like Escherichia coli.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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