Quality Segment
assay
≥97% (HPLC)
form
powder
color
white to yellow
antibiotic activity spectrum
viruses
mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
C1=C(N=C(C(=O)N1)C(=O)N)F
InChI
InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
InChI key
ZCGNOVWYSGBHAU-UHFFFAOYSA-N
General description
Favipiravir is a pyrazinecarboxamide derivative which is an RNA polymerase inhibitors. Favipiravir is converted to the ribofuranosyltriphosphate derivative by host enzymes and selectively inhibits the influenza viral RNA-dependent RNA polymerase. Favipiravir has broad-spectrum activity against RNA viruses, including influenza viruses, arena viruses, bunyaviruses, and flaviviruses.
Biochem/physiol Actions
Favipiravir inhibits the RNA-dependent RNA polymerase enzyme, which is essential for the replication of RNA viruses such as influenza and SARS-CoV-2 (the virus that causes COVID-19). Inhibition of RNA-dependent RNA polymerase activity leads to the disruption of viral RNA replication and ultimately, the reduction of viral load.
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signalword
Warning
hcodes
Hazard Classifications
Muta. 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable