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SBR00082

Isepamicin Sulfate

Name: Isepamicin Sulfate
Brand: SIGMA

≥68%, powder

Synonym(s):

Isepamicin monosulfate, Isepamicin sulfate

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₄₅N₅O₁₆S

CAS Number:

67814-76-0

Molecular Weight:

667.68

UNSPSC Code:

51101500

NACRES:

NA.41

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Properties

Quality Segment

100

assay

≥68%

form

powder

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

advanced drug delivery

mode of action

protein synthesis | inhibits

storage temp.

2-8°C

SMILES string

C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N)NC(=O)[C@H](CN)O)O.OS(=O)(=O)O

InChI

InChI=1S/C22H43N5O12.H2O4S/c1-22(35)6-36-20(15(33)18(22)26-2)39-17-8(27-19(34)9(28)4-23)3-7(25)16(14(17)32)38-21-13(31)12(30)11(29)10(5-24)37-21;1-5(2,3)4/h7-18,20-21,26,28-33,35H,3-6,23-25H2,1-2H3,(H,27,34);(H2,1,2,3,4)/t7-,8+,9-,10+,11+,12-,13+,14-,15+,16+,17-,18+,20+,21+,22-;/m0./s1

InChI key

DDXRHRXGIWOVDQ-MGAUJLSLSA-N

Description

General description

Isepamicin Sulfate is a semisynthetic aminoglycoside antibiotic derived from gentamicin with a spectrum of activity against Gram-positive bacteria, Gram-negative bacteria, and fungi.

Biochem/physiol Actions

Sepamicin Sulfate inhibits bacterial protein synthesis by binding to the bacterial 30S ribosomal subunit, leading to the misreading of genetic information and inhibition of protein synthesis, and ultimately, bacterial cell death.

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319

Precautionary Statements

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)