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Merck
CN

SBR00086

Remdesivir

≥98% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):
C27H35N6O8P
CAS Number:
Molecular Weight:
602.58
UNSPSC Code:
51101500
NACRES:
NA.41
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

antibiotic activity spectrum

viruses

mode of action

DNA synthesis | inhibits

shipped in

ambient

SMILES string

CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

InChI

1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1

InChI key

RWWYLEGWBNMMLJ-YSOARWBDSA-N

General description

Remdesiviris is an antibioitic which belongs to the class of compounds known as nucleotide analogues. Remdesivir has broad spectrum antiviral activity against RNA viruses.

Biochem/physiol Actions

Remdesivir inhibits viral RNA synthesis, which is essential for the replication of RNA viruses. Remdesivir is a nucleotide analogue, which means that it is designed to mimic the structure of natural nucleotides, the building blocks of RNA and DNA. When remdesivir is incorporated into the viral RNA by the viral RNA polymerase, it terminates RNA synthesis prematurely, preventing further replication of the viral RNA. This leads to the inhibition of viral replication and the reduction of viral load, which can help to reduce the severity of viral infections. Remdesivir has been shown to be active against a broad range of RNA viruses, including coronaviruses, filoviruses, and paramyxoviruses, among others.


pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

STOT RE 2 Oral

target_organs

Kidney

Storage Class

11 - Combustible Solids

wgk

WGK 3



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Global Trade Item Number

SKUGTIN
SBR00086-10MG04065271157422