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Merck
CN

SBR00091

Sulbenicillin Sodium

≥95% (H-NMR), powder

Synonym(s):

Sulfobenzylpenicillin, Sulfocillin

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About This Item

Empirical Formula (Hill Notation):
C16H16N2Na2O7S2
CAS Number:
28002-18-8
Molecular Weight:
458.42
UNSPSC Code:
51101500
NACRES:
NA.21

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InChI

1S/C16H18N2O7S2.2Na/c1-16(2)11(15(21)22)18-13(20)9(14(18)26-16)17-12(19)10(27(23,24)25)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,17,19)(H,21,22)(H,23,24,25);;/q;2*+1/p-2/t9-,10?,11+,14-;;/m1./s1

InChI key

FWRNIJIOFYDBES-HCIBPFAFSA-L

SMILES string

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(C3=CC=CC=C3)S(=O)(=O)[O-])C(=O)[O-])C.[Na+].[Na+]

assay

≥95% (H-NMR)

form

powder

color

white to light yellow

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | inhibits

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

Sulbenicillin Sodium is an antibiotic which belongs to a group of compounds known as penicillin antibiotics. Sulbenicillin Sodium is a combination of sulbactam and ampicillin. Sulbactam is a beta-lactamase inhibitor that works by binding to bacterial beta-lactamase enzymes, which are produced by some Gram-negative and Gram-positive bacteria to inactivate beta-lactam antibiotics including penicillins. By inhibiting the activity of beta-lactamase enzymes, sulbactam restores the activity of ampicillin against susceptible bacteria, thereby enhancing the spectrum and potency of the antibiotic.

Biochem/physiol Actions

Sulbenicillin Sodium inhibits bacterial cell wall synthesis and the inhibition of beta-lactamase enzymes that would otherwise inactivate the penicillin antibiotic.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000381681
0000381681

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