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About This Item
Empirical Formula (Hill Notation):
C16H16N2Na2O7S2
CAS Number:
Molecular Weight:
458.42
UNSPSC Code:
51101500
NACRES:
NA.21
InChI
1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3
InChI key
QTYCMDBMOLSEAM-UHFFFAOYSA-N
SMILES string
CC1([C@@H](N2[C@H](S1)[C@@](C2=O)(NC(=O)C(C3=CSC=C3)C(=O)O)OC)C(=O)O)C
assay
≥80% (HPLC)
form
powder
color
white to yellow
antibiotic activity spectrum
Gram-negative bacteria
mode of action
cell wall synthesis | inhibits
shipped in
ambient
storage temp.
2-8°C
Quality Level
General description
Temocillin disodium is an aminoglycoside antibiotic which inhibits protein synthesis.
Biochem/physiol Actions
Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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