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Merck
CN

SBR00092

Temocillin Disodium

≥80% (HPLC), powder

Synonym(s):

Ipconazole

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About This Item

Empirical Formula (Hill Notation):
C16H16N2Na2O7S2
CAS Number:
Molecular Weight:
458.42
UNSPSC Code:
51101500
NACRES:
NA.21
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InChI

1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3

InChI key

QTYCMDBMOLSEAM-UHFFFAOYSA-N

SMILES string

CC1([C@@H](N2[C@H](S1)[C@@](C2=O)(NC(=O)C(C3=CSC=C3)C(=O)O)OC)C(=O)O)C

assay

≥80% (HPLC)

form

powder

color

white to yellow

antibiotic activity spectrum

Gram-negative bacteria

mode of action

cell wall synthesis | inhibits

shipped in

ambient

storage temp.

2-8°C

Quality Level

General description

Temocillin disodium is an aminoglycoside antibiotic which inhibits protein synthesis.

Biochem/physiol Actions

Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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