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About This Item
Empirical Formula (Hill Notation):
C16H16N2Na2O7S2
CAS Number:
Molecular Weight:
458.42
UNSPSC Code:
51101500
NACRES:
NA.21
Quality Segment
assay
≥80% (HPLC)
form
powder
color
white to yellow
antibiotic activity spectrum
Gram-negative bacteria
application(s)
advanced drug delivery
mode of action
cell wall synthesis | inhibits
shipped in
ambient
storage temp.
2-8°C
SMILES string
CC1([C@@H](N2[C@H](S1)[C@@](C2=O)(NC(=O)C(C3=CSC=C3)C(=O)O)OC)C(=O)O)C
InChI
1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3
InChI key
QTYCMDBMOLSEAM-UHFFFAOYSA-N
General description
Temocillin disodium is an aminoglycoside antibiotic which inhibits protein synthesis.
Biochem/physiol Actions
Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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