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Merck
CN

SBR00099

Tebipenem Pivoxyl

≥98% (HPLC)

Synonym(s):

TBPM-PI

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About This Item

Empirical Formula (Hill Notation):
C22H31N3O6S2
CAS Number:
Molecular Weight:
497.63
UNSPSC Code:
51101500
NACRES:
NA.41
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Quality Segment

assay

≥98% (HPLC)

mp

135 °C

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

advanced drug delivery

mode of action

cell wall synthesis | inhibits

shipped in

ambient

storage temp.

−20°C

SMILES string

CC1[C@H]2C(C(=O)N2C(=C1SC3CN(C3)C4=NCCS4)C(=O)OCOC(=O)C(C)(C)C)C(C)O

InChI

1S/C22H31N3O6S2/c1-11-15-14(12(2)26)18(27)25(15)16(19(28)30-10-31-20(29)22(3,4)5)17(11)33-13-8-24(9-13)21-23-6-7-32-21/h11-15,26H,6-10H2,1-5H3/t11-,12-,14-,15-/m1/s1

InChI key

SNUDIPVBUUXCDG-QHSBEEBCSA-N

General description

Tebipenem pivoxil is a antibiotic which belongs to the class of compounds known as carbapenem antibiotics. Tebipenem is active against a wide range of Gram-negative and Gram-positive bacteria, including Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, and Haemophilus influenzae, among others.

Biochem/physiol Actions

Tebipenem inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the formation of the peptidoglycan layer of the bacterial cell wall by binding to penicillin-binding proteins (PBPs) on the bacterial cell surface. This leads to the weakening and eventual lysis of the bacterial cell.


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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