SCP0002
Acetyl-Amyloid β 25-35
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About This Item
Empirical Formula (Hill Notation):
C47H83N13O15S1
Molecular Weight:
1102.31
NACRES:
NA.32
UNSPSC Code:
12352202
General description
Amyloid-β (Aβ) peptides are a major component of the senile plaques characteristic of the Alzheimer brain. It is a type- I transmembrane protein. The amyloid β precursor protein is cleaved to amyloid peptides 36-43 amino acids in length. Aβ (25-35) represents the region that aggregates during plaque formation and is a functional domain implicated in both neurotrophic and neurotoxic effects. The gene encoding amyloid-β is localized on human chromosome 21. Acetylation may improve stability in in vitro and in vivo assays.
Application
Acetyl-Amyloid β 25-35 has been used to prepare rat models with Alzheimer′s disease.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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