SCP0005
MG-115 Peptide
≥95% (HPLC), lyophilized powder
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About This Item
Empirical Formula (Hill Notation):
C25H39N3O5
Molecular Weight:
461.59
UNSPSC Code:
12352202
NACRES:
NA.32
Product Name
MG-115 / ASD 4955,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Application
MG-115 (Z-Leu-Leu-Nva-al) is used as a selective proteosome inhibitor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Yolanda Pérez-Pertejo et al.
Parasitology, 138(9), 1082-1092 (2011-08-05)
Methionine adenosyltransferase (MAT) is an important enzyme for metabolic processes, to the extent that its product, S-adenosylmethionine (AdoMet), plays a key role in trans-methylation, trans-sulphuration and polyamine synthesis. Previous studies have shown that a MAT-overexpressing strain of Leishmania donovani controls
Estabelle Ang et al.
Journal of cellular physiology, 220(2), 450-459 (2009-04-15)
Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast formation
Karim Harhouri et al.
EMBO molecular medicine, 9(9), 1294-1313 (2017-07-05)
Hutchinson-Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point mutation in LMNA encoding A-type lamins. Progerin, a truncated and toxic prelamin A issued from aberrant splicing, accumulates in HGPS cells' nuclei
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