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Merck
CN

SCP0030

[Gly22]-Amyloid β 1-42 Arctic human

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About This Item

Empirical Formula (Hill Notation):
C200H307N55O58S1
Molecular Weight:
4441.98
NACRES:
NA.32
UNSPSC Code:
12352209
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... APP(351)

General description

β-Amyloid 1-42 is one of the major constituents of the neurofibrillary tangles and plaques characteristic of the Alzheimer brain. The Arctic mutation E22G causes early onset of Alzheimer′s compared to wild type and promotes protofibril formation and neurotoxicity.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Qiujian Yu et al.
Biological research, 51(1), 35-35 (2018-09-21)
The previous studies have demonstrated the reduction of thiamine diphosphate is specific to Alzheimer's disease (AD) and causal factor of brain glucose hypometabolism, which is considered as a neurodegenerative index of AD and closely correlates with the degree of cognitive



Global Trade Item Number

SKUGTIN
SCP0030-1MG04061826693148
SCP0030-500UG04061833024669