SCP0030
[Gly22]-Amyloid β 1-42 Arctic human
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About This Item
Empirical Formula (Hill Notation):
C200H307N55O58S1
Molecular Weight:
4441.98
NACRES:
NA.32
UNSPSC Code:
12352209
General description
β-Amyloid 1-42 is one of the major constituents of the neurofibrillary tangles and plaques characteristic of the Alzheimer brain. The Arctic mutation E22G causes early onset of Alzheimer′s compared to wild type and promotes protofibril formation and neurotoxicity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Qiujian Yu et al.
Biological research, 51(1), 35-35 (2018-09-21)
The previous studies have demonstrated the reduction of thiamine diphosphate is specific to Alzheimer's disease (AD) and causal factor of brain glucose hypometabolism, which is considered as a neurodegenerative index of AD and closely correlates with the degree of cognitive
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