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Merck
CN

SCP0041

[Ala28]-Amyloid β 25-35

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C42H74N12O14S1
CAS Number:
Molecular Weight:
1003.17
NACRES:
NA.32
UNSPSC Code:
12352209
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥68%

storage condition

protect from light

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... APP(351)

General description

β-Amyloid peptides are a major component of the senile placques characteristic of the Alzheimer brain. Aβ (25-35) represents the region that aggregates during placque formation in Alzheimer′s disease and is a functional domain implicated in both neurotrophic and neurotoxic effects. Substitutions in this sequence can contribute to an understanding of structural characteristics related to membrane insertion, aggregation and protfibril formation with subsequent neurotoxic effects.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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