Skip to Content
Merck
CN

Key Documents

View All Documentation

SCP0060

CGRP II 8-37 human / β CGRP 8-37 human

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C138H229N43O38S1
Molecular Weight:
3130.63
NACRES:
NA.32
UNSPSC Code:
12352200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Application

β-Calcitonin gene related peptide (β-CGRP) regulates cardiovascular homeostasis and nociception via G-coupled protein receptor (GCPR) calcitonin receptor-like receptor (CALCRL).
CGRP II 8-37 is used as a CGRP receptor antagonist.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MF0413

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Joseph J Lynch et al.
European journal of pharmacology, 623(1-3), 96-102 (2009-09-22)
The triptans, serotonin 5-HT(1B/1D) receptor agonists exemplified by sumatriptan, are a mainstay migraine therapy but have class labeling contraindicating their use in patients with coronary artery disease. Triptans constrict human coronary artery in vitro, and there are case reports of
Vince T Nguyen et al.
Peptides, 33(1), 77-82 (2011-11-24)
Cardiac epinephrine and calcitonin gene-related peptide (CGRP) are produced by intrinsic cardiac adrenergic cells (ICA cells) residing in human and animal hearts. ICA cells are neuroparicine cells expressing δ-opioid receptors (DOR). We hypothesized that δ-opioid stimulation of ICA cells enhances
Toomas Talme et al.
Journal of neuroimmunology, 196(1-2), 60-66 (2008-04-22)
CGRP significantly stimulated migration of non-activated and anti-CD3 activated T lymphocytes into a collagen matrix when present inside the collagen, whereas somatostatin-14, NPY, substance P, VIP, beta-endorphin and metenkephalin had no or little effect. The CGRP antagonist CGRP 8-37 abrogated
View All Related Papers

Global Trade Item Number

SKUGTIN
SCP0060-500UG04061833015544
SCP0060-1MG04061837017490