SCP0081
Caspase 3 Apopain Substrate
≥95% (HPLC), lyophilized
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About This Item
Empirical Formula (Hill Notation):
C30H34N5O13
Molecular Weight:
672.62
UNSPSC Code:
12352202
NACRES:
NA.32
Product Name
Caspase 3 Apopain Substrate,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥85%
storage condition
protect from light
storage temp.
−20°C
Application
Ac-DEVD-7-AFC (N-acetyl-asp-glu-val-asp-7-amino-4-trifluoromethyl coumarin) is used as a cell penetrating fluorogenic CED-related caspase substrate.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Caspase activation by anticancer drugs: the caspase storm.
Tao Z, Goodisman J, Penefsky HS, et al.
Molecular Pharmacology, 4, 583-595 (2007)
Benjawan Wudtiwai et al.
Journal of hematology & oncology, 4, 52-52 (2011-12-22)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells, but does not affect normal cells or human leukemic cells, such as MOLT-4 and U937 cells, which are relatively resistant to TRAIL. Three flavonoids extracted from the rhizome
Kateřina Kuželová et al.
Journal of cellular biochemistry, 112(11), 3334-3342 (2011-07-14)
The effects of the pan-caspase inhibitor Q-VD-OPh on caspase activity, DNA fragmentation, PARP cleavage, 7A6 exposition, and cellular adhesivity to fibronectin were analyzed in detail in three different apoptotic systems involving two cell lines (JURL-MK1 and HL60) and two apoptosis
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SCP0081-5MG | 04061833024775 |