SCP0087
Caspase 4 Inhibitor (ICH-2)
≥95% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C22H36N4O9
Molecular Weight:
500.54
NACRES:
NA.32
UNSPSC Code:
12352200
Product Name
Caspase 4 Inhibitor (ICH-2), ≥95% (HPLC)
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Related Categories
Application
Caspase 4 Inhibitor (Ac-LEVD-CHO) is used for the selective inhibition of caspase 4 to differentiate its role in specific cell apoptosis pathways.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Zong-Mei Bian et al.
Investigative ophthalmology & visual science, 50(12), 6006-6014 (2009-08-01)
To investigate the functional involvement of caspase-4 in human retinal pigment epithelial (hRPE) cells. Expression and activation of caspase-4 in hRPE cells were measured after stimulation with proinflammatory agents IL-1beta (2 ng/mL), TNF-alpha (20 ng/mL), lipopolysaccharide (1000 ng/mL), interferon-gamma (500
Akiko Yamamuro et al.
Journal of pharmacological sciences, 115(2), 239-243 (2011-02-02)
The present study investigated the function of caspase-4 in endoplasmic reticulum (ER) stress-induced apoptosis in human neuronal cell line SH-SY5Y. Tunicamycin, which is known to induce ER stress, activated both caspase-9 and caspase-4, and the activation of caspase-4 preceded that
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