SCP0091
Caspase 9 Substrate, chromogenic
≥95% (HPLC), lyophilized
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About This Item
Empirical Formula (Hill Notation):
C29H38N8O11
Molecular Weight:
674.66
UNSPSC Code:
12352202
NACRES:
NA.32
Product Name
Caspase 9 Substrate, chromogenic, ≥95% (HPLC)
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Application
Caspase 9 is an initiator caspase that cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(5), 539-546 (2011-06-22)
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Juan Liu et al.
Molecular cancer, 10, 95-95 (2011-08-02)
Caspase-8 is a key upstream mediator in death receptor-mediated apoptosis and also participates in mitochondria-mediated apoptosis via cleavage of proapoptotic Bid. However, the role of caspase-8 in p53- and p73-dependent apoptosis induced by genotoxic drugs remains unclear. We recently reported
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SCP0091-5MG | 04061837017537 |