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Merck
CN

SCP0106

Caspase Substrate, chromogenic

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About This Item

Empirical Formula (Hill Notation):
C27H39N7O10
Molecular Weight:
621.64
NACRES:
NA.32
UNSPSC Code:
12352200
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Application

Ac-VQVD-pNa (Acetyl-Val-Gln-Val-Asp-p-nitroanilide) is used as a chromogenic caspase substrate.


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Bin Fang et al.
Journal of molecular biology, 360(3), 654-666 (2006-06-20)
The molecular basis for the substrate specificity of human caspase-3 has been investigated using peptide analog inhibitors and substrates that vary at the P2, P3, and P5 positions. Crystal structures were determined of caspase-3 complexes with the substrate analogs at



Global Trade Item Number

SKUGTIN
SCP0106-5MG04061833266250