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Merck
CN

SCP0139

Caspase 8 Substrate, fluorogenic

≥95% (HPLC), lyophilized

Synonym(s):

Ac-VETD-AMC

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About This Item

Empirical Formula (Hill Notation):
C30H39N5O12
Molecular Weight:
661.66
UNSPSC Code:
12352202
NACRES:
NA.32
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Product Name

Caspase 8 Substrate, fluorogenic,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥67%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP8(841)

Application

Fluorogenic caspase 8 substrate has been used to measure caspase 8 activity in Jurkat cell lysates.

Biochem/physiol Actions

The peptide Ac-Val-Glu-Thr-Asp-AMC, or Ac-VETD-AMC, is a fluorogenic, modified peptide substrate for caspase 8.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Functional intersection of Human Defensin 5 with the TNF receptor pathway
WuyuanLu Erikde Leeuw
Febs Letters, 558(10) (2014)
T L Yue et al.
The Journal of biological chemistry, 274(3), 1479-1486 (1999-01-09)
TL1 is a recently discovered novel member of the tumor necrosis factor (TNF) cytokine family. TL1 is abundantly expressed in endothelial cells, but its function is not known. The present study was undertaken to explore whether TL1 induces apoptosis in
Apoptosis in polycystic kidney disease: involvement of caspases
Ali, S.M., et al.
The American Journal of Physiology, 278, R763-R769 (2000)



Global Trade Item Number

SKUGTIN
SCP0139-5MG04061837017582