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SCP0147

FR-1, cyclic

Name: FR-1, cyclic
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₃₅H₅₇N₁₃O₁₆S₂

Molecular Weight:

980.03

NACRES:

NA.32

UNSPSC Code:

12352202

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Properties

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥78%

storage condition

protect from light

storage temp.

−20°C

Description

Application

FR-1 is a cyclic RGDS peptide that acts via binding to FR-1 receptor, a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein involved in early embryogenesis.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

BH0601

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An RGDS peptide-binding receptor, FR-1R, localizes to the basal side of the ectoderm and to primary mesenchyme cells in sand dollar embryos.

H Katow et al.

Development, growth & differentiation, 43(5), 601-610 (2001-09-29)

Immunoblotting using polyclonal antibodies (pAb) raised against an FR-1 receptor (FR-1R), a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein, of the sand dollar Clypeaster japonicus showed that the pAb monospecifically bound to the protein. FR-1R was present in purified plasma membrane, suggesting

Histological distribution of FR-1, a cyclic RGDS-peptide, binding sites during early embryogenesis, and isolation and initial characterization of FR-1 receptor in the sand dollar embryo.