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About This Item
Empirical Formula (Hill Notation):
C44H61N13O13S1
Molecular Weight:
1012.10
UNSPSC Code:
12352200
NACRES:
NA.32
Product Name
MMP 2 / MMP 9 Substrate,
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥78%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg
Application
Matrix metalloproteinases (MMP) are a family of zinc-dependent endopeptidases that degrade matrix proteins. MMPs include collagenases, gelatinases, matrilysins, enamelysins, metalloelastases, stromelysins and other structural protein and receptor lysins. The activity of these enzymes is selectively inhibited or measured by appropriately labeled peptides. DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg (DNP-PLGMWSR), Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (DNP-PLGLWA-D-R-NH2), Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (DNP-PQGIAGQ-D-R-OH) and MOCAc [(7-methoxy coumarin-4-yl) acetyl]-RPKPYANvaWMK(Dnp[2,4-dinitrophenyl])-NH(2) are substrates for matrix metalloproteinase 2 and matrix metalloproteinase 9.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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