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SCP0224

Prostate Specific Antigen Substrate

≥95% (HPLC), lyophilized

Synonym(s):

KLK3, Kallikrein-related peptidase-3, PSA 

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About This Item

Empirical Formula (Hill Notation):
C44H64N12O13
Molecular Weight:
969.05
UNSPSC Code:
12352204
NACRES:
NA.32
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Product Name

Prostate Specific Antigen Substrate,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

General description

Prostate specific antigen (PSA) is a kallikrein-related serine peptidase that belongs to the chymotrypsin subfamily serine protease. It was originally found in human semen. PSA is also detected in serum correlated to benign and metastatic disease.

Application

Prostate Specific Antigen Substrate has been used to assay recombinant severe acute respiratory syndrome coronavirus-2 viral 3-chymotrypsin-like cysteine protease (SARS-CoV-2 3CLpro).

Biochem/physiol Actions

Prostate specific antigen (PSA). It exhibits chymotrypsin-like activity. PSA is the most abundant protease found in the prostate and secreted into the seminal fluid. It is a useful biomarker for prostate cancer. PSA digests the gel-forming proteins semenogelins I and II in semen. It shows antiangiogenic activity in vitro and in vivo.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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