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Merck
CN

SIL350

Silicic acid

BioReagent, suitable for column chromatography, 100-200 mesh (75 - 150 μm)

Synonym(s):

hydrated silica, metasilcic, silica acid

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About This Item

Empirical Formula (Hill Notation):
H2O3Si
CAS Number:
7699-41-4
Molecular Weight:
78.10
NACRES:
SB.54
PubChem Substance ID:
24899864
UNSPSC Code:
23201100
EC Number:
231-716-3
MDL number:
MFCD00054122

Key Documents

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Product Name

Silicic acid, BioReagent, suitable for column chromatography, 100-200 mesh (75 - 150 μm)

InChI key

IJKVHSBPTUYDLN-UHFFFAOYSA-N

InChI

1S/H2O3Si/c1-4(2)3/h1-2H

SMILES string

O[Si](O)=O

product line

BioReagent

assay

≥99.8% Si (as SiO2) basis

form

solid

particle size

100-200 mesh (75 - 150 μm)

suitability

suitable for column chromatography

Quality Level

100

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Application

For general chromatographic use.
Silicic acid has been used as a column material for the purification of polyunsaturated fatty acids, fatty acid methyl ester, nucleic acid extraction from Suillus bovinus and lipid fractionation from soy milk powder.
Silicic acid is used in protein chromatography. Silicic acid has been used in a study to demonstrate the anti-biofilm potential of a glycolipid surfactant produced by a tropical marine strain of Serratia marcescens. Silicic acid has also been used to study the antioxidant activity of fresh and processed Jalapeño and Serrano peppers.

Biochem/physiol Actions

Silicic acid polymers are employed in water treatment systems, drug encapsulation cum delivery and for soluble nanoparticle generation. Silicic acid interacts with aluminum and reduces its bioavailability. It is an effective antidote for aluminum poisoning.

Preparation Note

Acid-washed.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX0585
MKCT3569
MKCQ5197
MKCL0362
MKCC8767

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Leroy S Pakkiri et al.
Glycobiology, 15(3), 291-302 (2004-10-16)
Based on recent analytical and enzymological studies, a topological model for the role of alpha-D-mannosyl-(1-->3)-alpha-D-mannosyl-(1-->3)-diacylglycerol (Man(2)-DAG) as a lipid anchor precursor and mannosylphosphorylundecaprenol (Man-P-Und) as a mannosyl donor in the assembly of a membrane-associated lipomannan (LM) in Micrococcus luteus has
Marlena C Kruger et al.
Prostaglandins, leukotrienes, and essential fatty acids, 73(5), 327-334 (2005-09-13)
Experimental animal and human studies have indicated that long chain polyunsaturated fatty acids (LCPUFA) may enhance calcium absorption, reduce urinary calcium excretion, and increase bone calcium content. In the present study, the effect of LCPUFA, as provided in evening primrose
Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion
Reffitt DM, et al.
Journal of Inorganic Biochemistry, 76(2), 141-147 (1999)
Emilio Alvarez-Parrilla et al.
Journal of agricultural and food chemistry, 59(1), 163-173 (2010-12-04)
In this research, total phenols, flavonoids, capsaicinoids, ascorbic acid, and antioxidant activity (ORAC, hydroxyl radical, DPPH, and TEAC assays) of fresh and processed (pickled and chipotle canned) Jalapeño and Serrano peppers were determined. All fresh and processed peppers contained capsaicin
<I>Suillus bovinus</I> glutamine synthetase gene organization, transcription and enzyme activities in the Scots pine mycorrhizosphere developed on forest humus.
Juuti, J.T., et al.
The New phytologist, 164(2), 389-399 (2004)
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