SMB00074
Viniferin
≥95% (LC/MS-ELSD)
Synonym(s):
(+)-ε-Viniferin
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C28H22O6
CAS Number:
Molecular Weight:
454.47
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25
Quality Level
assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
O1[C@@H]([C@H](c4c1cc(cc4\C=C\c5ccc(cc5)O)O)c3c(cc(cc3)O)O)c2ccc(cc2)O
InChI
1S/C28H22O6/c29-19-7-2-16(3-8-19)1-4-18-13-22(32)15-25-26(18)27(23-12-11-21(31)14-24(23)33)28(34-25)17-5-9-20(30)10-6-17/h1-15,27-33H/b4-1+/t27-,28+/m0/s1
InChI key
KQXXUMAWOUVEHD-BQYFGGCBSA-N
General description
Natural product derived from plant source.
Application
Viniferin has been used to study its effect on melanin production in melanocyte cultures.
Biochem/physiol Actions
Protein Huntingtin (Htt) mutation, reduces the SIRT3 (sirtuin 3) expression. Viniferin is known to offer protection against Htt mutation by reducing oxidative stress and preventing SIRT3 depletion, which is involved in energy metabolism. In vitro analysis showed that viniferin derivative could prevent amyloid β peptide aggregation.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
trans-(−)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease
Fu J, et al.
The Journal of Biological Chemistry, 287(29) (2012)
Advances in Chorea Research and Treatment (2013)
Protective effect of varepsilon-viniferin on beta-amyloid peptide aggregation investigated by electrospray ionization mass spectrometry
Richard T, et al.
Bioorganic & Medicinal Chemistry, 19(10) (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SMB00074-1MG | 04061826168196 |