SMB00086
Columbin
≥95% (LC/MS-ELSD)
Synonym(s):
Isocolumbin
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assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
C[C@@]12C[C@H](OC(=O)[C@@H]1CC[C@]3(C)[C@H]2[C@@H]4OC(=O)[C@@]3(O)C=C4)c5ccoc5
InChI
1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13+,14-,15-,18+,19+,20-/m0/s1
InChI key
AALLCALQGXXWNA-QJNFORGASA-N
General description
Natural product derived from plant source.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Siddig Ibrahim Abdelwahab et al.
European journal of pharmacology, 678(1-3), 61-70 (2012-01-10)
Columbin, a diterpenoid furanolactone, was isolated purely for the first time from the plant species Tinspora bakis. The anti-inflammatory effects of columbin were studied in vitro, in silico and in vivo. The effect of columbin on nitric oxide was examined
K Wada et al.
Biological & pharmaceutical bulletin, 18(4), 634-636 (1995-04-01)
In a screening series of bioactive components in edible and medicinal plants, we found that Calumbae Radix (Colombo root, 1% powdered feed, for 5 d) and its component, columbin (20-40 mg/kg/d, for 5 d, orally), shortened the sleeping time induced
A J Nok et al.
Journal of enzyme inhibition and medicinal chemistry, 17(1), 55-59 (2002-10-09)
The inhibitory effects of a naturally occurring diterpenoid furanolactone, columbin, on partially purified acidic phospholipase A2 (PLA2) from Naja nigricolis was investigated. Columbin inhibited the N. nigricolis PLA2 in a dose related pattern with an IC50 value of 2.5 microM.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SMB00086-1MG | 04061826168301 |