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Merck
CN

SMB00093

Pipernonaline

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About This Item

Empirical Formula (Hill Notation):
C21H27NO3
CAS Number:
Molecular Weight:
341.44
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
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InChI

1S/C21H27NO3/c23-21(22-14-8-5-9-15-22)11-7-4-2-1-3-6-10-18-12-13-19-20(16-18)25-17-24-19/h6-7,10-13,16H,1-5,8-9,14-15,17H2/b10-6+,11-7+

SMILES string

O=C(\C=C\CCCC\C=C\c1ccc2OCOc2c1)N3CCCCC3

InChI key

PKLGRWSJBLGIBF-JMQWPVDRSA-N

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

General description

Natural product derived from plant source.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Seung Woong Lee et al.
Bioorganic & medicinal chemistry letters, 18(16), 4544-4546 (2008-08-02)
Eight alkamides 1-8 were isolated by bioassay-guided isolation of EtOH extracts of the fruits of Piper longum and Piper nigum (Piperaceae). Their structures were elucidated by spectroscopic analysis ((1)H, (13)C NMR, and ESI-MS) as follows: guineensine (1), retrofracamide C (2)
Zhuang Jin et al.
Phytotherapy research : PTR, 23(8), 1194-1196 (2009-01-28)
A bioassay-guided isolation of an ethanol extract of the fruit of Piper longum L. yielded piperlonguminine, piperine and pipernonaline, as the main antihyperlipidemic constituents. They exhibit appreciable antihyperlipidemic activity in vivo, which is comparable to that of the commercial antihyperlipidemic

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