SMB00580
Vitamin K4
≥98% (HPLC)
Synonym(s):
2-Methyl-1,4-naphthalenediol diacetate, Menadiol diacetate, Vitamin K diacetate, acetomenaphthone
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About This Item
Empirical Formula (Hill Notation):
C15H14O4
CAS Number:
Molecular Weight:
258.27
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352205
EC Number:
209-352-1
MDL number:
InChI key
RYWSYCQQUDFMAU-UHFFFAOYSA-N
InChI
1S/C15H14O4/c1-9-8-14(18-10(2)16)12-6-4-5-7-13(12)15(9)19-11(3)17/h4-8H,1-3H3
SMILES string
CC(OC1=CC(C)=C(OC(C)=O)C2=CC=CC=C21)=O
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white to off-white
storage temp.
2-8°C
Quality Level
General description
Vitamin K4 (VK4), also referred to as 2-methyl-1,4-naphthalenediyldiacetate, is a synthetic hydrophilic form of vitamin K that belongs to menadione family. It is a diacetate form of VK3.
Biochem/physiol Actions
Vitamin K4 elicits anti-cancer functionality and induces apoptosis in prostate carcinoma.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway.
Jiang Y
Pharmazie, 68, 442-448 (2013)
One-Pot Hydroacetylation of Menadione (Vitamin K3) to Menadiol Diacetate (Vitamin K4) by Heterogeneous Catalysis.
Dobrinescu C
Advanced Synthesis & Catalysis, 354, 1301-1306 (2012)
Yu Jiang et al.
Die Pharmazie, 68(6), 442-448 (2013-07-24)
Vitamin K4 (VK4) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It has been reported that several vitamin Ks had inhibitory effects on various cancer cells. However, there is no report about VK4s anticancer activity.
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