SMB00705
Sesamin
≥98% (HPLC)
Synonym(s):
Fagarol
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About This Item
Empirical Formula (Hill Notation):
C20H18O6
CAS Number:
Molecular Weight:
354.35
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
solubility
DMSO: 10 mg/mL
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5
InChI
1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
InChI key
PEYUIKBAABKQKQ-AFHBHXEDSA-N
General description
Sesamin is the most abundant lignan isolated from Sesamum indicum or sesame seeds and sesame oil.
Application
Sesamin has been used as a reference standard to study the activity of Cytochrome P450 enzyme sesamin synthase from Sesamum indicum L. in the conversion of pinoresinol to sesamin.
Biochem/physiol Actions
Non-competitive Δ5-desaturase inhibitor.
Sesamin presents multiple health benefits including hypocholesterolemic, anti-hypertensive, anti-carcinogenic, anti-aging, immunoregulatory, hypoglycemic, anti-thrombotic, hepatoprotective, and antioxidant activities. It has also been demonstrated to work synergistically with vitamin E against lipid peroxidation. Sesamin was found to be metabolized into several catechol forms in the liver. These cathecols have a potent ability to scavenge superoxide radicals.
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signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Mitsuo Namiki
Critical reviews in food science and nutrition, 47(7), 651-673 (2007-10-19)
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve
Sarah Dalibalta et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(10), 1276-1289 (2020-11-03)
Sesamin, a major lignin isolated from sesame (Sesamum indicum) seeds and sesame oil, is known to possess antioxidant and anti-inflammatory properties. Several studies have revealed that oxidative stress and inflammation play a major role in a variety of cardiovascular diseases
Colonoscope constriction and laser safety interlock problems investigated.
Today's OR nurse, 14(3), 48-48 (1992-03-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SMB00705-10MG | 04061834680833 |
| SMB00705-50MG | 04061834680840 |