SMB00914
Isovanillic Acid 3-Sulfate Disodium Salt
≥96% (HPLC)
Synonym(s):
Isovanillic acid 3-sulfate disodium salt
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About This Item
Empirical Formula (Hill Notation):
C8H6Na2O7S
CAS Number:
Molecular Weight:
292.17
UNSPSC Code:
12352205
NACRES:
NA.25
Quality Segment
assay
≥96% (HPLC)
form
powder
color
, White to off-white
solubility
water: 40 mg/mL
storage temp.
2-8°C
SMILES string
COC(C=C1)=C(OS(=O)(O[Na])=O)C=C1C(O[Na])=O
General description
Isovanillic acid 3-O-sulfate (IVAS) is a gut microbial phenolic metabolite primarily derived from consumed cyanidin 3-O-glucoside, a major compound in berry fruits. IVAS is the most effective among the gut microbial phenolic metabolites tested to enhance glucose uptake & metabolism in human skeletal muscle myoblast LHCN-M2. IIVAS is shown to increase glucose transport via GLUT4- and PI3K-dependent mechanisms. IVAS also upregulates GLUT1, GLUT4, PI3K p85a protein level, and Akt phosphorylation, establishing a novel link between gut microbiota, host diet and skeletal muscle energy source utilization.Also another study shows that IVAS restores glycosaminoglycans (GAGs) level and reduce inflammatory markers in diabetic human aortic endothelial cells (HAECs).
Other Notes
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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