SMB01013
Methyl 2,5-Dihydroxycinnamate
≥90% (LC/MS-ELSD)
Synonym(s):
2,4-Dihydroxymethylcinnamate, Methyl grevillate
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About This Item
Empirical Formula (Hill Notation):
C10H10O4
CAS Number:
Molecular Weight:
194.18
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.25
biological source
plant
Assay
≥90% (LC/MS-ELSD)
form
solid
mol wt
194.18
solubility
water: slightly soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
O(C)C(=O)C=Cc1c(ccc(c1)O)O
InChI
1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3
InChI key
BQCNSTFWSKOWMA-UHFFFAOYSA-N
Related Categories
General description
Methyl 2,5-dihydroxycinnamate, a hydroxycinnamic acid, is a bioactive natural compound commonly derived from plants like Azadirachta indica and Murraya paniculata. Current research indicates that this plant-derived metabolite may possess diverse biological activities, encompassing anti-inflammatory and antitumor properties. Furthermore, it serves as a human urinary metabolite, a geroprotector, and an inhibitor of EC 2.7.10.1 (receptor protein-tyrosine kinase). It is a cell-permeable analog of erbstatin, a natural substance found in Streptomyces, demonstrates inhibitory effects on the autophosphorylation of the epidermal growth factor receptor. Moreover, it acts as a competitive inhibitor of epidermal growth factor receptor-associated tyrosine kinase, effectively impeding v-abl tyrosine kinase activation. Additionally, Methyl 2,5-dihydroxycinnamate has been observed to induce apoptosis in mouse thymocytes and inhibit the G2/M phase of the cell cycle.
Application
Methyl 2,5-Dihydroxycinnamate is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Features and Benefits
- Suitable for Biochemical and Biomedical research
- Versatile and adaptable for wide variety of laboratory and research applications
Other Notes
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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