SMB01074
Sibiricose A5
≥85% (LC/MS-ELSD)
Synonym(s):
3-O-Feruloylsucrose
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About This Item
Empirical Formula (Hill Notation):
C22H30O14
CAS Number:
Molecular Weight:
518.47
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
SMILES string
O1[C@]([C@H]([C@@H]([C@H]1CO)O)OC(=O)\C=C\c3cc(c(cc3)O)OC)(O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)CO
InChI key
ZPEADZHVGOCGKH-YQTDNFGYSA-N
biological source
plant
assay
≥85% (LC/MS-ELSD)
form
solid
mol wt
518.47
solubility
water: slightly soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
Related Categories
General description
Sibiricose A5, a hydroxycinnamic acid, belongs to group of compounds known as phenylpropenoyl sucroses. This bioactive natural product is commonly available from Sibiricum sp., Polygala tenuifolia and Lilium speciosum plants. It exhibits various biological activities such as anti-inflammatory, anti-depressant, neuroprotective and anti-oxidant properties.
Application
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem/physiol Actions
Sibiricose A5 has potent antioxidant activity. It is a lactate dehydrogenase inhibitor, it displays antidepressant-like actions and it is active against Alzheimer′s disease.
Features and Benefits
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
Other Notes
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Xin Zhao et al.
Pharmaceutical biology, 58(1), 969-978 (2020-09-22)
Sibiricose A5 (A5), sibiricose A6 (A6), 3,6'-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. To compare the pharmacokinetics and bioavailability of
Hai-Hua Tu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(11), 1278-1280 (2008-10-04)
To investigate the antidepressant components of Polygala tenuifolia. The chromatographic method was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis, MTT method was applied to investigate their cytotoxic activities. Nine compounds were isolated
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