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Merck
CN

SMB01074

Sibiricose A5

≥85% (LC/MS-ELSD)

别名:

3-O-Feruloylsucrose

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关于此项目

经验公式(希尔记法):
C22H30O14
化学文摘社编号:
分子量:
518.47
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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SMILES string

O1[C@]([C@H]([C@@H]([C@H]1CO)O)OC(=O)\C=C\c3cc(c(cc3)O)OC)(O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)CO

InChI key

ZPEADZHVGOCGKH-YQTDNFGYSA-N

biological source

plant

assay

≥85% (LC/MS-ELSD)

form

solid

mol wt

518.47

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Sibiricose A5, a hydroxycinnamic acid, belongs to group of compounds known as phenylpropenoyl sucroses. This bioactive natural product is commonly available from Sibiricum sp., Polygala tenuifolia and Lilium speciosum plants. It exhibits various biological activities such as anti-inflammatory, anti-depressant, neuroprotective and anti-oxidant properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Sibiricose A5 has potent antioxidant activity. It is a lactate dehydrogenase inhibitor, it displays antidepressant-like actions and it is active against Alzheimer′s disease.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Xin Zhao et al.
Pharmaceutical biology, 58(1), 969-978 (2020-09-22)
Sibiricose A5 (A5), sibiricose A6 (A6), 3,6'-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. To compare the pharmacokinetics and bioavailability of
Hai-Hua Tu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(11), 1278-1280 (2008-10-04)
To investigate the antidepressant components of Polygala tenuifolia. The chromatographic method was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis, MTT method was applied to investigate their cytotoxic activities. Nine compounds were isolated

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