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Merck
CN

SMB01082

Licochalcone C

≥90% (LC/MS-ELSD)

Synonym(s):

(E)-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one, 4,4′-Dihydroxy-2-methoxy-3-prenylchalcone

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About This Item

Empirical Formula (Hill Notation):
C21H22O4
CAS Number:
144506-14-9
Molecular Weight:
338.40
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
MFCD20527293

Key Documents

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SMILES string

O(C)c1c(c(ccc1\C=C\C(=O)c2ccc(cc2)O)O)CC=C(C)C

InChI

1S/C21H22O4/c1-14(2)4-11-18-20(24)13-8-16(21(18)25-3)7-12-19(23)15-5-9-17(22)10-6-15/h4-10,12-13,22,24H,11H2,1-3H3/b12-7+

InChI key

WBDNTJSRHDSPSR-KPKJPENVSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

338.4

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

Related Categories

General description

Licochalcone C is a phenolic flavonoid belonging to the group of Chalcones and dihydrochalcones, commonly found in plants such as Glycyrrhiza inflata and Glycyrrhiza glabra. Existing research suggests that this plant-derived metabolite exhibits various biological activities, including cardioprotective, antibacterial, antioxidant, anti-inflammatory, and anti-apoptotic properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

According to the existing research, Licochalcone C may have an effect on processes related to inflammation and cell death regulation by inhibiting the expression of TNF-α, Caspase and Bcl-2/Bax

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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