SML0011
VAHA
≥98% (HPLC)
Synonym(s):
VAHA, Valproyl hydroxamic acid, VPA-HA
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About This Item
Empirical Formula (Hill Notation):
C8H17NO2
CAS Number:
Molecular Weight:
159.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
solubility
DMSO: ≥25 mg/mL
storage temp.
2-8°C
SMILES string
CCCC(CCC)C(=O)NO
InChI
1S/C8H17NO2/c1-3-5-7(6-4-2)8(10)9-11/h7,11H,3-6H2,1-2H3,(H,9,10)
InChI key
ROJGIRXXBBBMPL-UHFFFAOYSA-N
Application
VAHA may be used in cell signaling studies.
Biochem/physiol Actions
Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders.
VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity
VAHA is an HDAC inhibitor
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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