SML0154
SPV-106
≥98% (HPLC)
Synonym(s):
2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b
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About This Item
Empirical Formula (Hill Notation):
C22H40O4
CAS Number:
Molecular Weight:
368.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
oil
Quality Segment
assay
≥98% (HPLC)
form
oil
color
colorless
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC
InChI
1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3
InChI key
APIJHPAXMCKJBY-UHFFFAOYSA-N
Biochem/physiol Actions
Mixed histone acetylase inhibitor/activator
SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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