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Merck
CN

SML0154

SPV-106

≥98% (HPLC)

Synonym(s):

2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b

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About This Item

Empirical Formula (Hill Notation):
C22H40O4
CAS Number:
1036939-38-4
Molecular Weight:
368.55
NACRES:
NA.77
PubChem Substance ID:
329825202
UNSPSC Code:
12352200
MDL number:
MFCD20527327

Key Documents

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InChI

1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3

SMILES string

CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC

InChI key

APIJHPAXMCKJBY-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

oil

color

colorless

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Mixed histone acetylase inhibitor/activator
SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
084M4609V
073M4603V
091M4626V

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Articles

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We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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