SML0165
Fluorescent GABA-B receptor Antagonist (GB-633-AN) synthetic
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About This Item
Empirical Formula (Hill Notation):
C45H53N5O6PCl2F2BS
Molecular Weight:
942.68
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
assay
≥97% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
The SML0165 ligand was shown to antagonize the activity of the GABA-B agonist, GABA, in a recombinant CHO cell line expressing the human GABA-B1 and GABA-B2 receptors and a serum-responsive secreted placental alkaline phosphatase (SPAP) reporter gene.
Features and Benefits
This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Dissolve 0.2 mg in 21.2 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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