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Merck
CN

SML0168

Fluorescent Histamine H3/H4 receptor Antagonist (H3-633-AN) synthetic

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About This Item

Empirical Formula (Hill Notation):
C44H48BF2N8O3S2
Molecular Weight:
849.84
NACRES:
NA.77
UNSPSC Code:
12352200
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storage temp.

−20°C

Quality Segment

Biochem/physiol Actions

The SML0168 ligand was shown to antagonize the activity of the histamine agonist, histamine, in two separate recombinant CHO cell lines expressing either the human H2 or H3-receptor and a cyclic-AMP responsive secreted placental alkaline phosphatase (SPAP) reporter gene.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Dissolve 0.2 mg in 23.5 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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