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Merck
CN

SML0182

bPiDl hydrate

≥98% (HPLC)

Synonym(s):

1,1′-(1,10-decanediyl)bis[3-methyl-pyridinium iodide (1:2) hydrate, N,N-decane-1,10-diyl-bis-3-picolinium diiodide hydrate

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About This Item

Empirical Formula (Hill Notation):
C22H34I2N2 · xH2O
CAS Number:
525596-64-9
Molecular Weight:
580.33 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
329825211
UNSPSC Code:
12352202
MDL number:
MFCD21608520
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100

Key Documents

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InChI

1S/C22H34N2.2HI.H2O/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24;;;/h11-14,17-20H,3-10,15-16H2,1-2H3;2*1H;1H2/q+2;;;/p-2

SMILES string

O.[I-].[I-].Cc1ccc[n+](CCCCCCCCCC[n+]2cccc(C)c2)c1

InChI key

ILAREMIWZYIULF-UHFFFAOYSA-L

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

H2O: ≥10 mg/mL

storage temp.

2-8°C

Quality Level

100

Application

bPiDl hydrate may be used to study nicotinic receptor-mediated signaling.

Biochem/physiol Actions

bPiDI is an α6β2-specific antagonist that inhibits nicotine-evoked and endogenous dopamine release from rat striatal slices (IC50 = 150 nM, Imax = 55%). bPiDI treatment decreases nicotine self-administration, and nicotine-induced locomotor activity in rats.
bPiDl is a selective α6β2-specific nicotinic receptor antagonist

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000407614
045M4614V
101M4617V

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Articles

Acetylcholine Receptors (Nicotinic)

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