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Merck
CN

SML0182

bPiDl hydrate

≥98% (HPLC)

别名:

1,1′-(1,10-decanediyl)bis[3-methyl-pyridinium iodide (1:2) hydrate, N,N-decane-1,10-diyl-bis-3-picolinium diiodide hydrate

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关于此项目

经验公式(希尔记法):
C22H34I2N2 · xH2O
化学文摘社编号:
分子量:
580.33 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

H2O: ≥10 mg/mL

storage temp.

2-8°C

SMILES string

O.[I-].[I-].Cc1ccc[n+](CCCCCCCCCC[n+]2cccc(C)c2)c1

InChI

1S/C22H34N2.2HI.H2O/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24;;;/h11-14,17-20H,3-10,15-16H2,1-2H3;2*1H;1H2/q+2;;;/p-2

InChI key

ILAREMIWZYIULF-UHFFFAOYSA-L

Application

bPiDl hydrate may be used to study nicotinic receptor-mediated signaling.

Biochem/physiol Actions

bPiDI is an α6β2-specific antagonist that inhibits nicotine-evoked and endogenous dopamine release from rat striatal slices (IC50 = 150 nM, Imax = 55%). bPiDI treatment decreases nicotine self-administration, and nicotine-induced locomotor activity in rats.
bPiDl is a selective α6β2-specific nicotinic receptor antagonist

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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商品

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全球贸易项目编号

货号GTIN
SML0182-10MG04061832075105