SML0182
bPiDl hydrate
≥98% (HPLC)
别名:
1,1′-(1,10-decanediyl)bis[3-methyl-pyridinium iodide (1:2) hydrate, N,N-decane-1,10-diyl-bis-3-picolinium diiodide hydrate
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关于此项目
经验公式（希尔记法）:
C22H34I2N2 · xH2O
化学文摘社编号:
分子量:
580.33 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
InChI
1S/C22H34N2.2HI.H2O/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24;;;/h11-14,17-20H,3-10,15-16H2,1-2H3;2*1H;1H2/q+2;;;/p-2
SMILES string
O.[I-].[I-].Cc1ccc[n+](CCCCCCCCCC[n+]2cccc(C)c2)c1
InChI key
ILAREMIWZYIULF-UHFFFAOYSA-L
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
H2O: ≥10 mg/mL
storage temp.
2-8°C
Quality Level
Application
bPiDl hydrate may be used to study nicotinic receptor-mediated signaling.
Biochem/physiol Actions
bPiDI is an α6β2-specific antagonist that inhibits nicotine-evoked and endogenous dopamine release from rat striatal slices (IC50 = 150 nM, Imax = 55%). bPiDI treatment decreases nicotine self-administration, and nicotine-induced locomotor activity in rats.
bPiDl is a selective α6β2-specific nicotinic receptor antagonist
Features and Benefits
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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