SML0258
CPPG
≥98% (HPLC)
Synonym(s):
(R,S)-α-Cyclopropyl-4-phosphonophenylglycine
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About This Item
Empirical Formula (Hill Notation):
C11H14NO5P
CAS Number:
Molecular Weight:
271.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: >5 mg/mL
storage temp.
room temp
SMILES string
NC(C1CC1)(C(O)=O)c2ccc(cc2)P(O)(O)=O
InChI
1S/C11H14NO5P/c12-11(10(13)14,7-1-2-7)8-3-5-9(6-4-8)18(15,16)17/h3-7H,1-2,12H2,(H,13,14)(H2,15,16,17)
InChI key
IGODGTDUQSMDQU-UHFFFAOYSA-N
Biochem/physiol Actions
(R,S)-α-Cyclopropyl-4-phosphonophenylglycine (CPPG) can be used in combination with scopolamine to treat the depressive disorder.
CPPG is a potent group II/III metabotropic glutamate receptor antagonist, with approximately 20-fold selectivity for mGlu group III over group II (IC50 values of 2.2 and 46.2 nM respectively).
CPPG is a potent group II/III metabotropic glutamate receptor antagonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
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