SML0289
Bromfenac sodium
≥98% (HPLC), COX1 and COX2 inhibitor, powder
Synonym(s):
2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt
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About This Item
Empirical Formula (Hill Notation):
C15H11BrNNaO3
CAS Number:
Molecular Weight:
356.15
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Product Name
Bromfenac sodium, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
faintly yellow to dark yellow
solubility
H2O: ≥5 mg/mL
storage temp.
2-8°C
SMILES string
[Na+].Nc1c(CC([O-])=O)cccc1C(=O)c2ccc(Br)cc2
InChI
1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
InChI key
HZFGMQJYAFHESD-UHFFFAOYSA-M
Gene Information
human ... PTGS1(5742), PTGS2(5743)
Application
Bromfenac sodium has been used:
- to study its ability to bind to melanin
- in the synthesis of bromfenac indolinone standard
- to analyze its permeability in porcine conjunctiva
Biochem/physiol Actions
Bromfenac exhibits antipyretic and prostaglandin synthetase inhibiting properties. It has therapeutic properties against the reduction of ocular pain and inflammation in postoperative cataract patients. Bromfenac acts as an effective agent against allergic conjunctivitis. It has the potential to treat acute muscle pain, osteoarthritis, and rheumatoid arthritis.
Bromfenac is a nonsteroidal anti inflammatory drug (NSAID) that inhibits both COX1 and COX2. It is used as an opthalmic analgesic.
Bromfenac is a nonsteroidal anti inflammatory drug (NSAID); COX1 and COX2 inhibitor; opthalmic analgesic.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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