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SML0298

PSNCBAM-1

≥98% (HPLC)

Synonym(s):

N-(4-Chlorophenyl)-N′-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]-urea

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About This Item

Empirical Formula (Hill Notation):
C22H21ClN4O
CAS Number:
877202-74-9
Molecular Weight:
392.88
NACRES:
NA.77
PubChem Substance ID:
329825304
UNSPSC Code:
12352200
MDL number:
MFCD12756395
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

Clc1ccc(NC(=O)Nc2cccc(c2)-c3cccc(n3)N4CCCC4)cc1

InChI

1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)

InChI key

HDAYFSFWIPRJSO-UHFFFAOYSA-N

Biochem/physiol Actions

PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1.
PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1. The compound blocks the effects of WIN 55212-2 and CP55940, and reduces food intake and weight gain in rats.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
062M4743V

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Thomas F Gamage et al.
Neuropharmacology, 125, 365-375 (2017-08-15)
While allosteric modulators of the cannabinoid type-1 receptor (CB

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Cannabinoid Receptors

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Global Trade Item Number

SKUGTIN
SML0298-25MG04061832559810
SML0298-5MG04061832559827

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