SML0337
S-Allyl-L-cysteine
≥98% (HPLC), antioxidant, powder
Synonym(s):
L-Deoxyalliin, S-allyl-cysteine, S-allylcysteine, SAC
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About This Item
Empirical Formula (Hill Notation):
C6H11NO2S
CAS Number:
Molecular Weight:
161.22
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.77
Product Name
S-Allyl-L-cysteine, ≥98% (HPLC)
Quality Level
Assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -8 to -15°, c = 1 in H2O
color
white to beige
solubility
H2O: >10 mg/mL
storage temp.
−20°C
SMILES string
N[C@@H](CSCC=C)C(O)=O
InChI
1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
InChI key
ZFAHNWWNDFHPOH-YFKPBYRVSA-N
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General description
S-Allyl-L-cysteine has anti-inflammatory properties. It inhibits prooxidant enzymes and chelates metals. S-Allyl-L-cysteine exhibits hypoglycemic and cholesterol-lowering effects. It prevents apoptosis, lowers the activity of inducible nitric oxide synthase and blocks nuclear factor kappa B activity.
Biochem/physiol Actions
S-allyl-L-cysteine is a sulfur containing amino acid found in garlic with antioxidant, anti-cancer, antihepatotoxic, neuroprotective and neurotrophic activity.
S-allyl-L-cysteine is a sulfur containing amino acid found in garlic with antioxidant, anti-cancer, antihepatotoxic, neuroprotective and neurotrophic activity. S-allyl-L-cysteine has potent activity in several animal models of ischemic injury and Alzhemer′s disease.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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K Ried et al.
European journal of clinical nutrition, 67(1), 64-70 (2012-11-22)
Hypertension affects about 30% of adults worldwide. Garlic has blood pressure-lowering properties and the mechanism of action is biologically plausible. Our trial assessed the effect, dose-response, tolerability and acceptability of different doses of aged garlic extract as an adjunct treatment
Man-Hui Pai et al.
The British journal of nutrition, 108(1), 28-38 (2011-10-21)
Oral cancer is prevalent worldwide. Studies have indicated that an increase in the osteopontin (OPN) plasma level is correlated with the progression of oral cancer. Our previous report showed that the aqueous garlic extract S-allylcysteine (SAC) inhibited the epithelial-mesenchymal transition
Ana L Colín-González et al.
Oxidative medicine and cellular longevity, 2012, 907162-907162 (2012-06-12)
Aged garlic extract (AGE) is an odorless garlic preparation containing S-allylcysteine (SAC) as its most abundant compound. A large number of studies have demonstrated the antioxidant activity of AGE and SAC in both in vivo--in diverse experimental animal models associated
Marcelle B M Spera et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(1), 313-318 (2010-11-06)
Nuclear magnetic resonance studies, molecular modeling and antibacterial assays of the palladium(II) complex with S-allyl-L-cysteine (deoxyalliin) are presented. Studies based on solid and solution 13C and 15N nuclear magnetic resonance (NMR) spectroscopy confirmed that the palladium(II) complex preserved the same
Samir Mandal et al.
Biochimica et biophysica acta, 1820(1), 9-23 (2011-10-29)
Chronic lead (Pb(2+)) exposure leads to the reduced lifespan of erythrocytes. Oxidative stress and K(+) loss accelerate Fas translocation into lipid raft microdomains inducing Fas mediated death signaling in these erythrocytes. Pathophysiological-based therapeutic strategies to combat against erythrocyte death were
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