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SML0340

Hydroxy-Dynasore

Name: Hydroxy-Dynasore
Brand: SIGMA

≥98% (HPLC), dynamin inhibitor, powder

Synonym(s):

3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide, 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₁₄N₂O₅

CAS Number:

1256493-34-1

Molecular Weight:

338.31

UNSPSC Code:

12352200

PubChem Substance ID:

329825345

NACRES:

NA.77

MDL number:

MFCD23704787

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

protect from light

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Properties

Product Name

Hydroxy-Dynasore, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

faintly yellow to dark yellow

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O

InChI

1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+

InChI key

UAXHPUSKEWEOAP-DJKKODMXSA-N

Description

Biochem/physiol Actions

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor.

Other Notes

Air sensitive.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c