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SML0436

BNS-22

≥98% (HPLC)

Synonym(s):

8-[(3,4-Dihydro-2H-quinolin-1-yl)carbonyl]-5,7-dimethoxy-4-propyl-2H-chromen-2-one

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About This Item

Empirical Formula (Hill Notation):
C24H25NO5
CAS Number:
1151668-24-4
Molecular Weight:
407.46
NACRES:
NA.77
PubChem Substance ID:
329824719
UNSPSC Code:
12352200
MDL number:
MFCD22628799
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL (clear solution; warmed)

storage temp.

2-8°C

SMILES string

COC1=C2C(OC(C=C2CCC)=O)=C(C(N3C(C=CC=C4)=C4CCC3)=O)C(OC)=C1

InChI

1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3

InChI key

LRPUQCTZOSTSGL-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

BNS-22 is a DNA-topoisomerase II (TOPO2) catalytic inhibitor.
BNS-22 is a derivative of natural product GUT-70 isolated from the stem bark of Calophyllum brasiliense exhibits antiproliferative activity against human cancer cells. It appears that BNS-22 is a specific DNA-topoisomerase II (TOPO2) catalytic inhibitor. BNS-22 does not induce DNA damage.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
082M4601V

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Global Trade Item Number

SKUGTIN
SML0436-25MG04061832261171
SML0436-5MG04061833025666

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